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Vol. 16 No. 2 (2023)


Psychophysical Problems of Peri– and Postmenopausal Women – an Urgent Public Health Challenge

DOI:  [Google Scholar]
Published: 2023-12-29


The peri – and postmenopausal period is one-third of the average woman’s life. Despite its physiological nature, it is usually associated with a number of ailments that consequently weaken a woman’s psychophysical condition. The emergence of disorders in the psychological and somatic spheres can make it more difficult among women to perform social, domestic and professional functions, including those falling under labour law. The appearance of symptoms of anxiety and depression is much more common among women than men, and the duration of the COVID-19 epidemic has exacerbated health problems, often causing new difficulties especially in the aspect of mental health of postmenopausal women, creating a new and urgent challenge for state bodies responsible for prevention programs to create a comprehensive pilot project in this area of public health.


  1. Afshari, Fateme, Narjes Bahri, Moosa Sajjadi, et al. 2020. “Menopause uncertainty: the impact of two educational interventions among women during menopausal transition and beyond.” Menopause Rev 19(1):18-24. [Google Scholar]
  2. Albert, Paul. 2015. “Why is depression more prevalent in women?” J. Psychiatry Neurosci 40:219-21. [Google Scholar]
  3. Alkhamees, Abdulmajeed, Saleh Alrashed, Ali Alzunaydi, et al. 2020. “The psychological impact of COVID-19 pandemic on the general population of Saudi Arabia.” Compr. Psychiatry 102. [Google Scholar]
  4. Alvisi, Stefania, Giulia Gava, Isabella Orsili, et al. 2019. “Vaginal health in menopausal women.” Medicina 55(10):615. [Google Scholar]
  5. Avis, Nancy, Sybil Crawford, Gail Greendale, et al. 2015. “Duration of menopausal vasomotor symptoms over the menopause transition.” JAMA Intern Med 175(4):531-39. [Google Scholar]
  6. Babicki, Mateusz. and Agnieszka Mastalerz-Migas. 2020. “Występowanie zaburzeń lękowych wśród Polaków w dobie pandemii COVID-19.” Psychiatr. Pol 188:1-13. [Google Scholar]
  7. Baranowski, Włodzimierz, Romuald Dębski, Tomasz Paszkowski, et al. 2011. “Rekomendacje Polskiego Towarzystwa Menopauzy i Andropauzy dotyczące stosowania lokalnej terapii hormonalnej u kobiet w okresie menopauzy.” Menopause Review 10 (4):263-66. [Google Scholar]
  8. Benke, Christopher, Lara Autenrieth, Eva Asselmann, et al. 2020. “Lockdown, quarantine measures, and social distancing: Associations with depression, anxiety and distress at the beginning of the COVID-19 pandemic among adults from Germany.” Psychiatry Res 293. Doi: 10.1016/j.psychres.2020.113462 [Google Scholar]
  9. Brotman, Rebecca, Jacques Ravel, Richard Cone, et al. 2010. “Rapid fluctuation of the vaginal microbiota measured by Gram stain analysis.” Sex. Transm. Infect 86:297-302. [Google Scholar]
  10. Capobianco, Giampero, Jean Marie Wenger, Giovanni Battista Meloni, et al. 2014. “Triple therapy with Lactobacilli acidophili, estriol plus pelvic floor rehabilitation for symptoms of urogenital aging in postmenopausal women.” Arch Gynecol Obstet 289 (3):601-608. [Google Scholar]
  11. Cauci, Sabina, Silvia Driussi, Davide De Santo, et al. 2002. “Prevalence of bacterial vaginosis and vaginal flora changes in peri – and postmenopausal women.” J. Clin. Microbiol 40:2147-215. [Google Scholar]
  12. Wen Rui, Zhang, Kun, Wang, Lu Yin, et al. 2020. “Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China.” Psychother Psychosom 89:242-50. [Google Scholar]
  13. El Khoudary, Samar, and Rebecca Thurston. 2018. “Cardiovascular implications of the menopause transition: endogenous sex hormones and vasomotor symptoms.” Obstet Gynecol Clin N Am 45(4):64-61. [Google Scholar]
  14. Firat, Meryem, Ayse Okanli, Yalcin Kanbay, et al. 2021. “The prevalence of pandemic anxiety; anxiety and depression during the COVID-19 pandemic in Turkey.” Psychiatry Clin Psychopharmacol 31:198-205. [Google Scholar]
  15. Gliniewicz, Karol, Maria Schneider, Benjamin Ridenhour, et al. 2019. “Comparison of the vaginal microbiomes of premenopausal and postmenopausal women.” Front Microbiol 10:193. [Google Scholar]
  16. Gold, Ellen. 2011. “The timing of the age at which natural menopause occurs.” Obstet Gynecol Clin N Am 38(3):425-40. [Google Scholar]
  17. Gougeon, Aain, René Ecochard, and Jean Christophe Thalabard. 1994. “Age-related changes of the population of human ovarian follicles: increase in the disappearance rate of nongrowing and early-growing follicles in aging women.” Biol Reprod 50(3):653-63. [Google Scholar]
  18. Gracia, Clarisa R., and Ellen Freeman. 2018. “Onset of the menopause transition: the earliest signs and symptoms.” Obstet Gynecol Clin N Am 45(4):585-97. [Google Scholar]
  19. Guidozzi, Franco. 2013. “Sleep and sleep disorders in menopausal women.” Climacteric 16:214-19. [Google Scholar]
  20. Hamoda, Haitham, Nick Panay, Hugo Pedder, et al. 2020. “The British Menopause Society & Women’s Health Concern 2020 recommendations on hormone replacement therapy in menopausal women.” Post Reprod Health 26(4):181-209. [Google Scholar]
  21. Hansen, Karl, Nicholas Knowlton, Angela Thyer, et al. 2008. “A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause.” Hum Reprod 23(3):699-708. [Google Scholar]
  22. Harlow, Sioban, Margrery Gass, Janet Hall, et al. 2012. “Executive summary of the Stages of Reproductive Aging Workshop 10: addressing the unfinished agenda of staging reproductive aging.” Menopause 19(4):387-95. [Google Scholar]
  23. Hill, Kenneth. 1996. “The demography of menopause.” Maturitas 23(2):113-27. [Google Scholar]
  24. Hsu, Hsiu-Chin, and Mei-Hsiang Lin. 2005. “Exploring quality of sleep and its related factors among menopausal women.” J Nurs Res 13:153-64. [Google Scholar]
  25. Huang, Yeen, and Ning Zhao. 2020. “Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey.” Psychiatry Res 288. [Google Scholar]
  26. Jasik, Karolina, Urszula Jaślikowska, Marta Zbrojkiewicz, et al. 2016. “Czynniki związane z występowaniem depresji u dorosłych. Przegląd systematyczny literatury polskiej w latach 2009-2014.” J. Educ. Health Sport 6:297-318. [Google Scholar]
  27. Kaczmarek, Maria. 2007. “Określenie wieku menopauzy naturalnej w populacji polskich kobiet.” Prz Menopauz 2:77-82. [Google Scholar]
  28. Kalmbach, David, Philip Cheng, Todd Arnedt, et al. 2019. “Treating insomnia improves depression, maladaptive thinking, and hyperarousal in postmenopausal women: Comparing cognitive-behavioral therapy for insomnia (CBTI), sleep restriction therapy, and sleep hygiene education.” Sleep Med 55:124-34. [Google Scholar]
  29. Karlamangla, Arun, Margie Lachman, WeiJuan Han, et al. 2017. “Evidence for cognitive aging in midlife women: study of women’s health across the nation.” PLoS 12 (1). [Google Scholar]
  30. Kravitz, Howard M, Patrizia Ganz, Joyce Bromberger, et al. 2003. “Sleep difficulty in women at midlife: a community survey of sleep and the menopausal transition.” Menopause 10(1):19-28. [Google Scholar]
  31. Lei, Lei, Xiaoming Huang, Shuai Zhang, et al. 2020. “Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus People Unaffected by Quarantine During the COVID-19 Epidemic in Southwestern China.” Experiment 26. Doi: 10.12659/MSM.924609 [Google Scholar]
  32. Li, Yun, Qingsong Qin, Qimeng Sun, et al. 2020. “Insomnia and psychological reactions during the COVID-19 outbreak in China.” J Clin Sleep Med 16:1417-418. [Google Scholar]
  33. Mazza, Cristina, Eleonora Ricci, Silvia Biondi, et al. 2020. “A Nationwide Survey of Psychological Distress among Italian People during the COVID-19 Pandemic: Immediate Psychological Responses and Associated Factors.” Int J Environ Res Public Health 17:3165. [Google Scholar]
  34. Martín-Salinas, Carmen, and Ana Lopez-Sobaler. 2017. “Beneficios de la soja en la salud femenina [Benefits of soy in women’s health].” Nutr Hosp 15:34 (Suppl 4):36-40. [Google Scholar]
  35. Milton, Alyssa, Louise Ellis, Tracey Davenport, et al. 2017. “Comparison of Self-Reported Telephone Interviewing and Web-Based Survey Responses: Findings from the Second Australian Young and Well National Survey.” JMIR Mental Health 4 (3). [Google Scholar]
  36. Morssinkhof, Margot., D. W. van Wylick, Simone Priester-Vink, et al. 2020. “Associations between sex hormones, sleep problems and depression: A systematic review.” Neurosci Biobehav Rev 118:669-80. [Google Scholar]
  37. Naufel, Maria Fernanda, Cristina Frange, Monica Levy Andersen, et al. “Association between obesity and sleep disorders in postmenopausal women.” Menopause 25:139-44. [Google Scholar]
  38. O’Neill, Sheila, and John Eden. 2012. “The pathophysiology of menopausal symptoms.” Obstetrics. Gynaecology & Reproductive Medicine 22(3):63-69. [Google Scholar]
  39. Özdin, Selçuk, and Şükriye Bayrak Özdin. 2020. “Levels and predictors of anxiety; depression and health anxiety during COVID-19 pandemic in Turkish society: The importance of gender.” Int. J. Soc. Psychiatry 66:504-11. [Google Scholar]
  40. Pala, Seval Çalişkan, Alaettin Ünsal, Didem Arslantaş, et al. 2022. “Evaluation of depression, social support and quality of life in perimenopausal and postmenopausal women in semi-rural Turkey.” Psychogeriatrics 22:679-87. [Google Scholar]
  41. Paramsothy, Pangaja, Siobán D Harlow, Bin Nan, et al. 2017. “Duration of the menopausal transition is longer in women with young age at onset: the multiethnic Study of Women’s Health across the Nation.” Menopause 24(2):142-49. [Google Scholar]
  42. Pedrosa, Ana Luisa, Leticia Bitencourt, Ana Cláudia Fontoura Fróes, et al. 2020. “Emotional, behavioral, and psychological impact of the COVID-19 pandemic.” Front Psychol 11. [Google Scholar]
  43. Perger, Elisa, Paola Mattaliano, and Carolina Lombardi. 2019. “Menopause and Sleep Apnea.” Maturita 124:35-38. [Google Scholar]
  44. Roy, Subir, James C Caillouette, Tapon Roy, et al. 2004. “Vaginal pH is similar to follicle-stimulating hormone for menopause diagnosis.” Am J Obstet Gynecol 190:1272-277. [Google Scholar]
  45. Rumianowski, Bogdan, Agnieszka Brodowska, Beata Karakiewicz, et al. 2012. “Czynniki środowiskowe wpływające na wiek wystąpienia naturalnej menopauzy u kobiet.” Prz Menopauz 5:412-16. [Google Scholar]
  46. Santoro, Nanette, Cassandra Roeca, Brandilyn A. Peters, et al. 2021. “The menopause transition: signs, symptoms, and management options.” J Clin Endocrinol Metab 106(1):1-15. [Google Scholar]
  47. Santoro, Nanette, and Stewart Taylor. 2011. “Reproductive Hormones and the Menopause Transition.” Obstet Gynecol Clin North Am 38(3):455-66. [Google Scholar]
  48. Schoenaker, Danielle, Caroline A. Jackson, Jemma V. Rowlands, et al. 2014. “Socioeconomic position, lifestyle factors and age at natural menopause: a systematic review and meta-analyses of studies across six continents.” Int J Epidemiol 43(5):1542-562. [Google Scholar]
  49. Smith, Lee, Louis Jacob, Anita Yakkundi, et al. 2020. “Correlates of symptoms of anxiety and depression and mental wellbeing associated with COVID-19: A cross-sectional study of UK-based respondents.” Psychiatry Res 291. [Google Scholar]
  50. Szmuilowicz, Emily, JoAnn E Manson, Jacques E Rossouw, et al. 2011. “Vasomotor symptoms and cardiovascular events in postmenopausal women.” Menopause 18(6):603-10. [Google Scholar]
  51. Talaulikar, Vikram S. 2020. “Menopause transition: Physiology and symptoms.” Best practice & research. Clinical obstetrics & gynaecology 81:3-7. [Google Scholar]
  52. Wielgoś, Mirosław, Natalia Mazanowska, and Bronisława Pietrzak. 2013. “Zanikowe zapalenie pochwy: objawy, diagnostyka i leczenie.” 17(5):434-37. [Google Scholar]
  53. Wu, Kitty K, D Lee, Am Sze, et al. 2022. “Posttraumatic Stress, Anxiety, and Depression in COVID-19 Survivors.” East Asian Arch Psychiatry 32:5-10. [Google Scholar]
  54. Verma, Shankey, and Aditi Mishra. 2020. “Depression, anxiety, and stress and socio-demographic correlates among general Indian public during COVID-19.” Int J Soc Psychiatry 66:756-62. [Google Scholar]
  55. Vivian-Taylor, Josephine, and Martha Hickey. 2014. “Menopause and depression: is there a link?” Maturitas 79(2):142-46. [Google Scholar]
  56. Yazdkhasti, Mansoureh, Meryam Keshavarz, Es Merghaati Khoei, et al. 2012. “The Effect of Support Group Method on Quality of Life in Post-menopausal Women.” Iran J Public Health 41:78-84. [Google Scholar]
  57. Zhao, Di M, Chunqin Liu, Xiujuan Feng, et al. 2019. “Menopausal symptoms in different substages of perimenopause and their relationships with social support and resilience.” Menopause 26:233-39. [Google Scholar]
  58. Zhou, Shuang-Jiang, Li-Gang Zhang, Lei-Lei Wang, et al. 2020. “Prevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19.” Eur Child Adolesc Psychiatry 29(6):749-58. [Google Scholar]
  59. Zolfaghari, Sheida, Chun Yao, Cynthia Thompson, et al. 2020. “Effects of menopause on sleep quality and sleep disorders: Canadian longitudinal study on aging.” Menopause 27:295-304. [Google Scholar]


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