Despite various doctrinal disputes, one cannot deny the existence of the variability of the content of human rights. Only their ontological substance remains unchanged. The subject of this study is to define the determinants affecting the content of human rights. The purpose of this research is to describe individual determinants and how they can affect the definition of the content of human rights. The very volatility of the content of human rights does not mean their relativization or their detachment from the inherent dignity of the human being.